HerbX reduced infectious SARS-CoV-2, influenza A, RSV and dengue virus in independent laboratory testing
In a 30-minute direct-contact suspension assay conducted by an independent U.S. laboratory, HerbX reduced the infectious titer of all four viruses tested, by more than 99% for three of the four.
- SARS-CoV-2 COVID-19
- >99%
- Influenza A H1N1
- >99.9%
- RSV Respiratory syncytial virus
- >90%
- Dengue virus Type 2 (DENV-2)
- >99.9%
The panel spanned four virus families: Coronaviridae (SARS-CoV-2), Orthomyxoviridae (influenza A H1N1), Pneumoviridae (RSV) and Flaviviridae (DENV-2). All four are enveloped viruses. DENV-2, a mosquito-borne flavivirus, falls outside the respiratory indications for which HerbX is being developed.
Activity was observed in each of the four HerbX production lots tested, manufactured between 2024 and 2026. Consistent biological activity from lot to lot is a key consideration in the development of multi-component botanical drugs.
Reductions in infectious titer ranged from greater than 90% (RSV) to greater than 99.9% (influenza A and DENV-2). The assay measures direct inactivation of virus in suspension; it does not assess antiviral activity in infected cells or in vivo, and the results do not establish clinical efficacy. Further nonclinical and controlled clinical studies are required. HerbX is an investigational drug candidate and has not been approved by the FDA.